hrp0086p1-p450 | Fat Metabolism and Obesity P1 | ESPE2016

Severe Hypertriglyceridemia in Pediatric Oncology Patient

Grau Gema , Portillo Nancy , Almaraz Ricardo Lopez , Echebarria Aizpea , Adan Rosa , Rodriguez Amaia , Vela Amaia , Astigarraga Itziar , Rica Itxaso

Background: Severe Hypertriglyceridemia (HTG) defined as triglycerides (TG) in blood plasma higher than 1000 mg/dl is a rare condition in childhood. Its causes are classified as primary and secondary and among these last they include pharmacological causes. Steroids associated with some chemotherapy drugs, particularly asparaginase (Asp), are a combination with special risk.Objective and hypotheses: Describe the evolution of lipids profile in LLA patient...

hrp0086p2-p768 | Pituitary and Neuroendocrinology P2 | ESPE2016

10 Years Review of Endocrine Diseases in Spanish Patients Diagnosed with Primary Brain Tumors in a Tertiary Hospital

Portillo Nancy , Gonzalez Usune , Rubio Raquel , Ariza Miguel Garcia , Grau Gema , Vela Amaia , Rodriguez Amaia , Astigarraga Itziar , Rica Itxaso

Background: Pediatric Central Nervous System (CNS) neoplasms are the most frequent solid tumors in children. Since the increase in survival, the patients are in high risk of developing long term sequelae. Endocrinological sequelae may be due to the oncological disease itself but usually derived from the treatment received, and they affect 20–50% of patients long-term. We aimed to review our experience from 2005 to 2015.Objective and hypotheses: Desc...